Experiencing a 'natural' high from sports, music, yoga, or just plain laughter, is one of the joys of human existence. This program describes the role of the brain's reward pathways and how neurotransmitters such as dopamine, serotonin, and endorphins influence feelings of pleasure. It tackles the issue of using so-called 'natural' drugs like marijuana. Looking at the drug from a neuroscientist's point of view, viewers will see how marijuana can cause a surge of dopamine and actually change the natural chemistry of the brain, causing toxicity, addiction, behaviour changes, and memory loss. Case studies contrast the experiences of young people who have learned to experience 'highs' from healthy pursuits versus recovering marijuana addicts to reinforce the message.